Can we cure HIV with an injection?

HIV was thought to be incurable, but after undergoing risky stem cell transplant surgeries, several patients no longer exhibit the deadly virus. Scientist Dr. Hans-Peter Kiem takes that idea a step further and shares his pioneering research using new gene-editing techniques. His bold vision may one day allow patients anywhere in the world to receive a single injection to stop HIV and other deadly diseases in their tracks.

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In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TED Talks video and live speakers combine to spark in-depth discussion and connection in a community setting. These events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.

Hans-Peter, the Director of the Stem Cell and Gene Therapy program at the Fred Hutchinson Cancer Research Center, is known as a pioneer in the development of new gene-editing technologies. Through his work as an oncologist providing bone marrow transplants to leukemia patients, Dr. Kiem learned it’s possible to modify genes in blood marrow stem cells and convey those genetic changes to a patient.

Hans-Peter and his team hope to achieve cures for diseases like HIV, cancer, sickle cell anemia, and other blood disorders with this ability to repair or modify genes by editing stem cells to carry healthier or disease-resistant versions of genes before transplant. He is currently pioneering “in vivo” and “ex vivo” approaches to make gene therapy and gene editing more broadly available and accessible to those living with HIV, especially in resource-limited settings.

He received his M.D. and Ph.D., at the University of Ulm in Germany. Hans-Peter came to the United States in 1988 and completed research at Stanford University. He received a degree in internal medicine at Vanderbilt University before an oncology fellowship at the University of Washington led to his work with the Fred Hutch.

This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

Dr. Hans-Peter Kiem, the Director of the Stem Cell and Gene Therapy program at the Fred Hutchinson Cancer Research Center, is known as a pioneer in the development of new gene-editing technologies. Through his work as an oncologist providing bone marrow transplants to leukemia patients, Dr. Kiem learned it’s possible to modify genes in blood marrow stem cells and convey those genetic changes to a patient.

Dr. Kiem and his team hope to achieve cures for diseases like HIV, cancer, sickle cell anemia and other blood disorders with this ability to repair or modify genes by editing stem cells to carry healthier or disease-resistant versions of genes prior to transplant. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

Topics

Health, Science,

Dr. Hans-Peter Kiem

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In the spirit of ideas worth spreading, TED has created a program called TEDx. TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. Our event is called TEDxSeattle, where x = independently organized TED event. At our TEDxSeattle event, TEDTalks video and live speakers will combine to spark deep discussion and connection in a small group. The TED Conference provides general guidance for the TEDx program, but individual TEDx events, including ours, are self-organized.